I got it working on my Linux (Ubuntu 20.04) desktop, but had to change a monitor setting to fix a serious playability glitch. I don’t know whether it’s specific to running it under Wine (other Unity/Windows games have worked fine for me on this machine without adjustment), or if it could happen on any dual-monitor setup. In either case, here’s the problem description and the fix.
Problem: The game has a horrible flicker, starting at the title screen. There’s no settings menu I can find to change refresh rate, and the flickering is so bad I can’t look at the screen for more than a couple of minutes without eyestrain.
Fix: In system settings, set both monitors to 59.95fps refresh rate.